Serum CCL18 is predictive for lung disease progression and mortality in systemic sclerosis
نویسندگان
چکیده
منابع مشابه
Serum CCL18 is predictive for lung disease progression and mortality in systemic sclerosis.
While we accept that there is a group of ILD patients in whom a specific ILD diagnosis is not possible, despite all efforts, we wish to encourage respiratory physicians to pursue an accurate ILD diagnosis, rather than accepting a diagnosis of unclassifiable ILD without full and accurate investigation. Although this is a tempting option, particularly in the absence of ready access to MDD, it is ...
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Background: Systemic sclerosis is an autoimmune disease affecting connective tissues, (including epidermal, subepidermal, microvasculature, etc.), leading to various extent of end-organ damage. The leading cause of mortality among these patients is lung involvement. The cardiovascular events happen more frequently in patients suffering systemic scleroderma, comparing to healthy population. This...
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OBJECTIVE To evaluate the prognostic value of bronchoalveolar lavage (BAL) cellular profiles in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD). METHODS BAL cellularity was examined in relation to mortality (n = 141), serial pulmonary function findings (n = 134), and "progression-free survival" (n = 134), by proportional hazards analysis. Baseline severity was ...
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Title Clinical association of serum interleukin 17 levels in systemic sclerosis: Is systemic sclerosis a Th17 disease? Author(s) Murata, Maki; Fujimoto, Manabu; Komura, Kazuhiro; Matsushita, Takashi; Hamaguchi, Yasuhito; Hasegawa, Minoru; Sato, Shinichi; Takehara, Kazuhiko Citation Journal of Dermatological Science, 50(3), pp.240-242; 2008 Issue Date 2008-03-07 URL http://hdl.handle.net/10069/1...
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Interstitial lung disease and pulmonary hypertension (PH) are the most common cardiopulmonary findings in patients with systemic sclerosis (SSc). About two thirds of patients suffering from SSc develop scleroderma interstitial lung disease. PH is present in about 20% of SSc patients and is typically associated with severe lung disease, although it may be an isolated manifestation of SSc. High-r...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2014
ISSN: 0903-1936,1399-3003
DOI: 10.1183/09031936.00131713